For the purpose of determinating the normal values of some parameters relevant to lead exposure, a study was carried out from April 1 to June 30, 1986 on 258 healthy Korean adults who have had no apparant lead exposure.
The lead indices subjected to this study were as follows; blood lead (PbB), hemoglobin (Hb), zinc protoporphyrin in blood (ZPP), delta-aminolevulinic acid dehydratase (ALAD) activity in blood, coproporphyrin in urine (CPU), delta-aminolevulinic acid in urine (ALAU).
1) The mean value of PbB was 17.17±7.87 ug/100 ml, and there was no statistically significant difference by age & sex. The distribution of PbB fitted to the log-normal distribution (x2=7.38, p>0.1).
2) The mean value of Hb in male (15.17±1.56 g/100 ml) was higher than in female (13.22±1.51 g/100 ml)(p<0.01). The distribution of Hb fitted to the normal distribution (x2=9.40, p>0.1).
3) The mean ´value of ZPP was 32.61±8.78 pg/100 ml, and there warms o-statistically significant difference by age & sex. The distribution of ZPP fitted to the normal distribution (x2=13.93, p>0.05). The correlation of ZPP & ALAD (r=-0.229), CPU (r=0.183) was statistically significant respectively.
4) The mean value of ALAD was 30.20 ±10.96 pmol ALA/min/L of R.B.C., and´ there was no statistically significant difference by age &.sex. The distribution of ALAD activity did not fit to the normal distribution. The correlation between ALAD & PbB (r= -0.219) was statistically significant.
5) The mean value of CPU was 36.10±24.54 pg/L, and there was no statistically significant difference by age & sex. The distribution of CPU did not fit to the normal distribution. The correlation between CPU & PbB (r=0.185), ZPP (r=0.183) was statistically signinificant respectively.
6) The mean value of ALAU was 1.94 ±0.96 mg/L, and there was no statistically significant difference by age & sex. The distribution of ALAU fitted to the normal distribution (x2=9.76, p>0.1).
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